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Washington, July 29 (ANI): A new study has suggested that antioxidants could play a key role in addressing infertility issues in both women and men, including erectile dysfunction.

new analysis noted that previous studies on the potential for antioxidants to help address this serious and growing problem have been inconclusive, but that other data indicates nutritional therapies may have significant potential.

Tory Hagen, in the Linus Pauling Institute at Oregon State University, and Francesco Visioli, lead author of the study at the Madrid Institute for Advanced Studies in Spain, also observed that infertility problems are often an early indicator of other degenerative disease issues such as atherosclerosis, high blood pressure and congestive heart failure. The same approaches that may help treat infertility could also be of value to head off those problems, they said.

"If oxidative stress is an underlying factor causing infertility, which we think the evidence points to, we should be able to do something about it," said Hagen, the Jamieson Chair of Healthspan Research in the Linus Pauling Institute.

"This might help prevent other critical health problems as well, at an early stage when nutritional therapies often work best," he added.

The results from early research have been equivocal, Hagen said, but that may be because they were too small or did not focus on antioxidants. Laboratory and in-vitro studies have been very promising, especially with some newer antioxidants such as lipoic acid that have received much less attention.

"The jury is still out on this," Hagen said.

"But the problem is huge, and the data from laboratory studies is very robust, it all fits. There is evidence this might work, and the potential benefits could be enormous," added Hagen.

If new approaches were developed successfully, the researchers said, they might help treat erectile dysfunction in men, egg implantation and endometriosis in women, and reduce the often serious and sometimes fatal condition of pre-eclampsia in pregnancy. The quality and health of semen and eggs might be improved.

The study has been published online in the journal Pharmacological Research. (ANI)

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新華社華盛頓 7月29日（ANI）：一項新的研究表明，抗氧化劑可以發揮關鍵作用，解決不育問題的婦女和男子，包括勃起功能障礙。
新的分析指出，以往的研究對潛在的抗氧化劑，以幫助解決這個日益嚴重的問題尚無定論，但其他數據表明營養療法可能有巨大的潛力。
保守黨的哈根，在萊納斯波林研究所在俄勒岡州立大學和弗朗切斯科Visioli，主要作者的研究在馬德里高等研究院在西班牙，還觀察到不育的問題往往是早期指標的其他退行性疾病問題，如動脈粥樣硬化，高血壓和充血性心力衰竭。同樣的方法，可能有助於治療不孕症也有利用價值，以阻止這些問題，他們說。
“如果氧化應激是導致不孕症的一個基本因素，我們認為證據表明，我們應該可以做一些事情吧，”哈根說，在賈米森講座 Healthspan研究的萊納斯波林研究所。
“這可能有助於預防其它嚴重的健康問題，以及在早期階段，當營養療法往往效果最好，”他補充說。
從早期的研究結果已經模棱兩可，哈根說，但是這可能是因為它們太小或不注重抗氧化劑。實驗室和體外研究已經非常看好，特別是一些較新的抗氧化劑如硫辛酸已經受到很大關注較少。
“陪審團仍然列於這一點，”哈根說。
“但問題是巨大的，從實驗室研究的數據是非常強大的，它適合所有有證據表明這可能是工作，而潛在的好處可能是巨大的，補充說：”哈根。
如果研製成功的新方法，研究人員說，他們可能幫助治療勃起功能障礙的男性，雞蛋植入和子宮內膜異位症的婦女，並減少經常嚴重，有時甚至致命的疾病先兆子癇的妊娠。質量和健康的精液和卵子可能得到改善。
這項研究已經發表在雜誌上藥理學研究。 （ANI）

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